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尊龙凯时 PEG系列抗体简介

发布时间:2025-03-10   信息来源:尊龙凯时官方编辑

一、产品名称

尊龙凯时推出的Anti-PEGAntibody,亦称为PEG抗体。

尊龙凯时 PEG系列抗体简介

二、产品描述

尊龙凯时的PEG(聚乙二醇)是一种由重复的乙二醇单元构成的化合物,其特点包括高亲水性、无毒性及无抗原性,具备良好的生物兼容性。PEG化修饰能显著改变药物的物理化学性质,延长血浆半衰期和吸收时间,同时影响药物与细胞受体的结合亲和力,提高肿瘤靶向性。在PEG化修饰药物的研发中,抗PEG抗体作为重要的研究工具,可以监测药物的药代动力学,如分布、代谢与排泄,同时还可用于聚乙二醇化蛋白质或分子(如纳米颗粒)的质量控制。

尊龙凯时的Antibodysystem PEG系列抗体适用于ELISA、WB和HC等实验。

三、相关产品

  • Anti-PEGAntibody(E112#)(RGK24701)
  • Anti-PEGAntibody(6A9/PEG2)(RGK24702)
  • Anti-PEGAntibody(14B5/PEG1a)(RGK24703)
  • Anti-PEGAntibody(14B5/PEG1b)(RGK24704)
  • Anti-PEGAntibody(331)(RGK24705)
  • Anti-PEGAntibody(2B5)(RGK24706)
  • Anti-PEGAntibody(32D6)(RGK24707)
  • Anti-PEGAntibody(AGP3)(RGK24708)
  • Anti-PEGAntibody(63)(RGK24709)
  • Anti-PEGAntibody(15-2b)(RGK24710)

四、产品详情

Anti-PEGAntibody(E112#)(RGK24701)

  • 别名:PEG, Poly(ethyleneglycol), Polyethyleneglycol
  • 货号:RGK24701
  • 宿主:Mouse
  • 同种型:IgG1, kappa
  • 克隆类型:Monoclonal
  • 靶标:PEG, Poly(ethyleneglycol), Polyethyleneglycol
  • 浓度:1mg/ml
  • 内毒素水平:请与实验室联系获取相关信息
  • 纯度:95%(依据SDS-PAGE测定)
  • 纯化方式:Protein A/G 纯化自细胞培养上清液
  • 克隆号:E112#
  • 应用:ELISA, WB
  • 状态:Liquid
  • 保存溶液:0.01 M PBS, pH 7.4
  • 稳定性和存储:使用手动解冻冰箱,避免反复冻融。短期存储于4°C(1-2周),长期存储于-20°C(12个月)或-80°C。

五、参考文献

  • PMID: 27369864 - Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation
  • PMID: 26118102 - "PEG dilemma" for liposomes and its solving approaches
  • PMID: 31336703 - Chemistry Routes for Copolymer Synthesis Containing PEG for Targeting, Imaging, and Drug Delivery Purposes
  • PMID: 37355210 - Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route
  • PMID: 39702782 - Exosome isolation based on polyethylene glycol (PEG): a review
  • PMID: 39012983 - Quantitation of PEG on PEGylated Gold Nanoparticles Using Reversed Phase High-Performance Liquid Chromatography and Charged Aerosol Detection
  • PMID: 25547369 - PEG-lipid micelles as drug carriers: physiochemical attributes, formulation principles and biological implication
  • PMID: 26191379 - Safety Evaluation of Polyethylene Glycol (PEG) Compounds for Cosmetic Use
  • PMID: 38469811 - Free PEG Suppresses Anaphylaxis to PEGylated Nanomedicine in Swine
  • PMID: 35079293 - Stepwise PEG synthesis featuring deprotection and coupling in one pot
  • PMID: 32024289 - The Importance of Poly(ethyleneglycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation
  • PMID: 34401032 - Missing PEG tube found at the ileocecal valve
  • PMID: 30694626 - Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice
  • PMID: 1458545 - The uses and properties of PEG-linked proteins
  • PMID: 36641121 - Accelerated clearance by antibodies against methoxy PEG depends on pegylation architecture

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