一、产品名称

尊龙凯时推出的Anti-PEGAntibody，亦称为PEG抗体。

二、产品描述

尊龙凯时的PEG（聚乙二醇）是一种由重复的乙二醇单元构成的化合物，其特点包括高亲水性、无毒性及无抗原性，具备良好的生物兼容性。PEG化修饰能显著改变药物的物理化学性质，延长血浆半衰期和吸收时间，同时影响药物与细胞受体的结合亲和力，提高肿瘤靶向性。在PEG化修饰药物的研发中，抗PEG抗体作为重要的研究工具，可以监测药物的药代动力学，如分布、代谢与排泄，同时还可用于聚乙二醇化蛋白质或分子（如纳米颗粒）的质量控制。

尊龙凯时的Antibodysystem PEG系列抗体适用于ELISA、WB和HC等实验。

三、相关产品

• Anti-PEGAntibody(E112#)(RGK24701)
• Anti-PEGAntibody(6A9/PEG2)(RGK24702)
• Anti-PEGAntibody(14B5/PEG1a)(RGK24703)
• Anti-PEGAntibody(14B5/PEG1b)(RGK24704)
• Anti-PEGAntibody(331)(RGK24705)
• Anti-PEGAntibody(2B5)(RGK24706)
• Anti-PEGAntibody(32D6)(RGK24707)
• Anti-PEGAntibody(AGP3)(RGK24708)
• Anti-PEGAntibody(63)(RGK24709)
• Anti-PEGAntibody(15-2b)(RGK24710)

四、产品详情

Anti-PEGAntibody(E112#)(RGK24701)

• 别名：PEG, Poly(ethyleneglycol), Polyethyleneglycol
• 货号：RGK24701
• 宿主：Mouse
• 同种型：IgG1, kappa
• 克隆类型：Monoclonal
• 靶标：PEG, Poly(ethyleneglycol), Polyethyleneglycol
• 浓度：1mg/ml
• 内毒素水平：请与实验室联系获取相关信息
• 纯度：95%（依据SDS-PAGE测定）
• 纯化方式：Protein A/G 纯化自细胞培养上清液
• 克隆号：E112#
• 应用：ELISA, WB
• 状态：Liquid
• 保存溶液：0.01 M PBS, pH 7.4
• 稳定性和存储：使用手动解冻冰箱，避免反复冻融。短期存储于4°C（1-2周），长期存储于-20°C（12个月）或-80°C。

五、参考文献

• PMID: 27369864 - Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation
• PMID: 26118102 - "PEG dilemma" for liposomes and its solving approaches
• PMID: 31336703 - Chemistry Routes for Copolymer Synthesis Containing PEG for Targeting, Imaging, and Drug Delivery Purposes
• PMID: 37355210 - Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route
• PMID: 39702782 - Exosome isolation based on polyethylene glycol (PEG): a review
• PMID: 39012983 - Quantitation of PEG on PEGylated Gold Nanoparticles Using Reversed Phase High-Performance Liquid Chromatography and Charged Aerosol Detection
• PMID: 25547369 - PEG-lipid micelles as drug carriers: physiochemical attributes, formulation principles and biological implication
• PMID: 26191379 - Safety Evaluation of Polyethylene Glycol (PEG) Compounds for Cosmetic Use
• PMID: 38469811 - Free PEG Suppresses Anaphylaxis to PEGylated Nanomedicine in Swine
• PMID: 35079293 - Stepwise PEG synthesis featuring deprotection and coupling in one pot
• PMID: 32024289 - The Importance of Poly(ethyleneglycol) Alternatives for Overcoming PEG Immunogenicity in Drug Delivery and Bioconjugation
• PMID: 34401032 - Missing PEG tube found at the ileocecal valve
• PMID: 30694626 - Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice
• PMID: 1458545 - The uses and properties of PEG-linked proteins
• PMID: 36641121 - Accelerated clearance by antibodies against methoxy PEG depends on pegylation architecture

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